Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06710.1Protein of unknown function DUF192; KEGG: hvo:HVO_0645 hypothetical protein; manually curated; PFAM: Protein of unknown function DUF192. (115 aa)    
Predicted Functional Partners:
AEN06709.1
KEGG: hbo:Hbor_25640 hypothetical protein.
       0.810
AEN06167.1
KEGG: hvo:HVO_1134 hypothetical protein.
  
     0.543
AEN07201.1
PFAM: Protein of unknown function DUF35; KEGG: nmg:Nmag_2476 protein of unknown function DUF35.
  
     0.537
AEN04741.1
PFAM: Major facilitator superfamily MFS-1; KEGG: hla:Hlac_1455 major facilitator superfamily MFS_1.
 
     0.511
AEN05976.1
KEGG: hbo:Hbor_18040 hypothetical protein.
  
     0.498
AEN07001.1
Transcriptional regulator, XRE family; SMART: Helix-turn-helix type 3; KEGG: hvo:HVO_2718 hypothetical protein.
 
     0.479
AEN04551.1
PFAM: Type II secretion system F domain; KEGG: hbo:Hbor_24640 hypothetical protein.
  
     0.472
AEN05492.1
PFAM: Protein of unknown function DUF87; KEGG: hbo:Hbor_07980 ATPase.
 
     0.453
AEN04961.1
KEGG: hvo:HVO_A0489 homocitrate synthase; PFAM: Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
       0.440
rad50
DNA double-strand break repair rad50 ATPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex. Belongs to the SMC family. RAD50 subfamily.
  
     0.440
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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