Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN06718.1CBS domain containing protein; PFAM: Cystathionine beta-synthase, core; KEGG: hla:Hlac_3545 CBS domain containing protein. (402 aa)    
Predicted Functional Partners:
AEN06609.1
Putative signal transduction protein with CBS domains; PFAM: Cystathionine beta-synthase, core; KEGG: hmu:Hmuk_0795 CBS domain containing protein.
  
    0.789
AEN06719.1
Hypothetical protein.
       0.773
AEN06720.1
Hypothetical protein.
       0.762
AEN05592.1
PFAM: UspA; KEGG: hje:HacjB3_06975 UspA domain protein.
  
    0.694
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 0.634
rps14
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles.
    
  0.595
AEN07143.1
PFAM: UspA; KEGG: hbo:Hbor_02280 universal stress protein UspA-like protein.
 
    0.590
AEN06733.1
TIGRFAM: Pyruvate kinase; KEGG: hma:rrnAC0546 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region; Belongs to the pyruvate kinase family.
  
 
 0.553
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.534
AEN06115.1
Ribosomal protein S5; KEGG: hla:Hlac_2429 30S ribosomal protein S5P; TIGRFAM: Ribosomal protein S5, eukaryotic/archaeal; PFAM: Ribosomal protein S5, N-terminal; Ribosomal protein S5, C-terminal; Belongs to the universal ribosomal protein uS5 family.
   
  0.526
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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