Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06734.1ROK family protein; PFAM: ROK; KEGG: hla:Hlac_0043 ROK family protein. (320 aa)    
Predicted Functional Partners:
pgi
KEGG: hbo:Hbor_05630 glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); PFAM: Phosphoglucose isomerase (PGI); Belongs to the GPI family.
 
 
 0.943
AEN06486.1
KEGG: hbo:Hbor_02570 phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, C-terminal; Belongs to the phosphohexose mutase family.
 
 
 0.930
gdh
Alcohol dehydrogenase GroES domain protein; Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway.
  
 
 0.846
AEN04522.1
PFAM: Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: hje:HacjB3_11450 fructose-bisphosphate aldolase.
 
  
  0.838
AEN06470.1
PFAM: NAD-dependent epimerase/dehydratase; KEGG: htu:Htur_4433 NAD-dependent epimerase/dehydratase.
 
  
 0.838
AEN05216.1
KEGG: htu:Htur_2421 hydroxypyruvate reductase; PFAM: MOFRL.
    
  0.821
aroA
Phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
    
  0.814
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
    
  0.809
AEN07077.1
NAD-dependent epimerase/dehydratase; Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
    
 0.809
AEN04840.1
PFAM: FAD dependent oxidoreductase; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Glucose-methanol-choline oxidoreductase, C-terminal; KEGG: hsl:OE2509R oxidoreductase-like protein.
    
  0.806
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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