Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN06776.1Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS; PFAM: Signal transduction response regulator, receiver region; PAS fold-4; PAS fold; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; KEGG: hma:rrnAC0848 HTR-like protein; SMART: Signal transduction response regulator, receiver region; PAS; PAC motif; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like. (929 aa)    
Predicted Functional Partners:
AEN05474.1
Transcriptional regulator, ModE family; KEGG: hma:rrnAC3264 molybdenum-binding protein; TIGRFAM: Molybdenum-pterin binding; PFAM: Transport-associated OB, type 1; HTH transcriptional regulator, LysR.
 
  
  0.819
AEN06076.1
PFAM: ABC-2 type transporter; KEGG: hbo:Hbor_21840 ABC multidrug transporter, permease component.
 
 
  0.818
AEN04794.1
KEGG: hje:HacjB3_09775 3-hydroxybutyryl-CoA dehydratase; PFAM: Crotonase, core; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.809
AEN05129.1
Enoyl-CoA hydratase; KEGG: hbo:Hbor_18480 short chain enoyl-CoA hydratase; PFAM: Crotonase, core; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.809
AEN05239.1
PFAM: Crotonase, core; KEGG: htu:Htur_1610 enoyl-CoA hydratase/isomerase.
  
 0.809
AEN07147.1
PFAM: Crotonase, core; KEGG: hje:HacjB3_15681 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.809
AEN06848.1
Polyamine-transporting ATPase; PFAM: ABC transporter-like; KEGG: hbo:Hbor_00690 ABC cobalt transporter ATPase; SMART: ATPase, AAA+ type, core.
  
 
  0.786
AEN05115.1
TIGRFAM: O-succinylbenzoate-CoA ligase; KEGG: hbo:Hbor_18630 O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase/ligase.
  
 0.765
AEN05817.1
KEGG: hla:Hlac_1800 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region.
 
 
 0.719
AEN05780.1
PFAM: Alpha/beta hydrolase fold-1; KEGG: hvo:HVO_2702 putative hydrolase.
   
 0.636
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (12%) [HD]