Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06777.1PFAM: Heat shock protein Hsp20; KEGG: hje:HacjB3_08020 HSP20-type molecular chaperone; Belongs to the small heat shock protein (HSP20) family. (143 aa)    
Predicted Functional Partners:
AEN06778.1
PFAM: Heat shock protein Hsp20; KEGG: hvo:HVO_0451 HSP20-type molecular chaperone; Belongs to the small heat shock protein (HSP20) family.
 
  
 
0.952
AEN07270.1
PFAM: Heat shock protein Hsp20; KEGG: hvo:HVO_0482 HSP20-type molecular chaperone.
     
0.932
AEN04641.1
PFAM: Heat shock protein Hsp20; KEGG: hla:Hlac_2381 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
     
  0.900
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 0.578
AEN06776.1
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS; PFAM: Signal transduction response regulator, receiver region; PAS fold-4; PAS fold; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like; KEGG: hma:rrnAC0848 HTR-like protein; SMART: Signal transduction response regulator, receiver region; PAS; PAC motif; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like.
   
 
 0.556
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 
 0.528
AEN05365.1
Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.452
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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