Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEN06790.1KEGG: hbo:Hbor_00410 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00268; PFAM: Asparagine synthase; tRNA methyl transferase-like. (292 aa)    
Predicted Functional Partners:
AEN05574.1
TIGRFAM: Protein of unknown function DUF111; HAMAP: UPF0272 protein; KEGG: hma:rrnAC1529 hypothetical protein; PFAM: Protein of unknown function DUF111; Belongs to the LarC family.
  
 0.932
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
    0.767
AEN04648.1
PFAM: Ribonuclease H; KEGG: hla:Hlac_0307 ribonuclease H.
 
      0.705
mutS2
DNA mismatch repair protein MutS domain protein; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
       0.674
AEN06789.1
Hypothetical protein.
       0.590
AEN04719.1
TIGRFAM: Cysteine desulfurase, SufS; KEGG: hbo:Hbor_34450 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; NIF system FeS cluster assembly, NifU, N-terminal.
       0.441
AEN06395.1
PFAM: Cation/H+ exchanger; KEGG: hje:HacjB3_06465 sodium/hydrogen exchanger.
  
    0.439
AEN06346.1
PFAM: Chlorite dismutase; Antibiotic biosynthesis monooxygenase; KEGG: hbo:Hbor_04740 hypothetical protein.
       0.402
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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