STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutS2DNA mismatch repair protein MutS domain protein; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. (656 aa)    
Predicted Functional Partners:
rnp2
Ribonuclease P protein component 2; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
  
     0.560
mutL
DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
  
 0.556
thrS
KEGG: hla:Hlac_1764 threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; TGS; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.533
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
   
 0.524
AEN06344.1
Peptidase M50; KEGG: hwa:HQ1095A metalloprotease/metallo peptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF.
 
     0.515
AEN04653.1
PHP domain protein; KEGG: hvo:HVO_0741 DNA polymerase X; PFAM: PHP, C-terminal; Helix-hairpin-helix motif; SMART: Polymerase/histidinol phosphatase, N-terminal; DNA-directed DNA polymerase, family X; Helix-hairpin-helix DNA-binding motif, class 1.
 
  
 0.507
AEN05274.1
PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; Ribosomal protein S1, RNA binding domain; KEGG: hla:Hlac_1616 nucleic acid binding OB-fold tRNA/helicase-type.
  
     0.504
AEN07254.1
PFAM: Protein of unknown function DUF88; KEGG: hla:Hlac_1242 protein of unknown function DUF88.
  
 
   0.499
AEN06790.1
KEGG: hbo:Hbor_00410 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00268; PFAM: Asparagine synthase; tRNA methyl transferase-like.
       0.497
AEN06856.1
Protein of unknown function UPF0153; PFAM: Uncharacterised protein family UPF0153; KEGG: hvo:HVO_0770 hypothetical protein.
  
     0.484
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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