Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06792.1KEGG: htu:Htur_0338 phosphodiesterase, MJ0936 family; TIGRFAM: Uncharacterised protein family UPF0025; PFAM: Metallophosphoesterase. (174 aa)    
Predicted Functional Partners:
AEN07051.1
Transcriptional regulator, XRE family; KEGG: nph:NP5106A ATP-dependent DNA helicase (intein-containing); PFAM: DNA-dependent ATPase MCM; Helix-turn-helix type 3; SMART: DNA-dependent ATPase MCM; Hedgehog/intein hint, N-terminal; Helix-turn-helix type 3; Hedgehog/intein hint domain, C-terminal; Belongs to the MCM family.
       0.826
AEN06793.1
KEGG: hbo:Hbor_29450 cation diffusion facilitator family transporter; TIGRFAM: Cation efflux protein; PFAM: Cation efflux protein.
 
     0.804
AEN06363.1
Nucleoside-triphosphatase; KEGG: hbo:Hbor_04980 ditpase; PFAM: Ham1-like protein.
  
  
 0.596
AEN06393.1
KEGG: hbo:Hbor_05260 hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00341; PFAM: Protein of unknown function DUF389.
     
 0.574
purO
IMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP.
 
     0.569
AEN07077.1
NAD-dependent epimerase/dehydratase; Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
 
  0.479
AEN06794.1
KEGG: hbo:Hbor_00240 hypothetical protein.
       0.450
AEN04780.1
PFAM: NAD-dependent epimerase/dehydratase; KEGG: hla:Hlac_2573 NAD-dependent epimerase/dehydratase.
 
 
  0.445
tfb-3
Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
  
    0.443
AEN05593.1
KEGG: hbo:Hbor_11180 BirA, biotin-(acetyl-CoA-carboxylase) ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase; Helix-turn-helix, type 11; Biotin protein ligase, C-terminal.
       0.441
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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