Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trm1N(2),N(2)-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (384 aa)    
Predicted Functional Partners:
AEN06802.1
Ribonuclease BN; KEGG: hla:Hlac_2359 ribonuclease BN; TIGRFAM: Ribonuclease BN; PFAM: Ribonuclease BN-related.
       0.804
AEN06151.1
PFAM: Pre-mRNA processing ribonucleoprotein, binding region; KEGG: hvo:HVO_1670 nucleolar protein-like protein.
 
    0.785
truB
tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
  
 
 0.779
pus10
Conserved hypothetical protein CHP01213; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
  
   
 0.739
AEN07053.1
KEGG: hla:Hlac_2541 hypothetical protein.
       0.730
AEN06596.1
PFAM: Putative RNA methylase; KEGG: htu:Htur_0132 putative RNA methylase.
  
 
 0.685
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
  
 
 0.682
AEN06513.1
KH domain protein; KEGG: hbo:Hbor_00890 universal archaeal kh domain protein; TIGRFAM: KH domain protein, archaea; SMART: K Homology.
  
    0.674
AEN06391.1
Small GTP-binding protein; KEGG: hbo:Hbor_05240 GTPase; TIGRFAM: Small GTP-binding protein; PFAM: Nucleolar GTP-binding 1.
 
   0.665
flpA
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
 
   0.663
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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