Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN06816.1PFAM: Prokaryotic chromosome segregation/condensation protein ScpA; KEGG: hbo:Hbor_25300 condensin subunit scpa. (343 aa)    
Predicted Functional Partners:
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
   
 0.957
AEN06818.1
KEGG: hvo:HVO_0688 hypothetical protein.
       0.907
AEN05564.1
PFAM: Protein of unknown function DUF63; KEGG: hwa:HQ2794A hypothetical protein.
  
     0.641
AEN06573.1
PFAM: Protein of unknown function DUF2072, Zinc-ribbon; KEGG: hvo:HVO_3012 hypothetical protein.
  
     0.634
AEN06344.1
Peptidase M50; KEGG: hwa:HQ1095A metalloprotease/metallo peptidase; PFAM: Peptidase M50; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF.
 
  
 0.633
AEN06489.1
Peptidase A24B, FlaK domain protein; PFAM: Peptidase A24B, preflagellin, C-terminal; Peptidase A24A, prepilin type IV; KEGG: hla:Hlac_2136 peptidase A24A prepilin type IV.
  
    0.627
rad50
DNA double-strand break repair rad50 ATPase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex. Belongs to the SMC family. RAD50 subfamily.
     
 0.605
AEN06410.1
PRC-barrel domain protein; PFAM: PRC-barrel; KEGG: hvo:HVO_1964 PRC-barrel domain-containing protein.
  
     0.580
AEN04504.1
PFAM: Methyltransferase type 12; KEGG: hbo:Hbor_19120 methyltransferase family protein.
  
     0.578
pcn
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
 
  
 0.571
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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