Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06844.1KEGG: hvo:HVO_0253 SUA5/YciO/YrdC/YwlC family protein; TIGRFAM: Sua5/YciO/YrdC/YwlC; PFAM: Sua5/YciO/YrdC, N-terminal. (194 aa)    
Predicted Functional Partners:
AEN06365.1
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.
 
 0.982
AEN06842.1
PFAM: Glutaredoxin; KEGG: hma:rrnAC2599 glutathione S-transferase.
       0.862
AEN06843.1
PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: hje:HacjB3_04100 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen.
       0.862
AEN06841.1
Protein of unknown function DUF21; KEGG: hwa:HQ3705A CBS domain-containing protein; PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated region; SMART: Cystathionine beta-synthase, core.
       0.681
thrS
KEGG: hla:Hlac_1764 threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; TGS; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.606
rsmA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
 
  
 0.534
AEN05593.1
KEGG: hbo:Hbor_11180 BirA, biotin-(acetyl-CoA-carboxylase) ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase; Helix-turn-helix, type 11; Biotin protein ligase, C-terminal.
 
    0.510
AEN06246.1
Histone acetyltransferase, ELP3 family; SMART: Elongator protein 3/MiaB/NifB; TIGRFAM: Histone acetyltransferase ELP3; KEGG: hla:Hlac_1480 histone acetyltransferase, ELP3 family; PFAM: Radical SAM; GCN5-related N-acetyltransferase.
 
   0.504
AEN05545.1
Methylase; KEGG: hbo:Hbor_12120 HemK-related methylase; TIGRFAM: Putative methylase; PFAM: Methyltransferase small.
  
  
 0.500
AEN05542.1
PFAM: Protein of unknown function DUF655; KEGG: hbo:Hbor_12150 RNA-binding protein.
      
 0.475
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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