STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN06865.1PFAM: Glutamine amidotransferase class-I, C-terminal; KEGG: hla:Hlac_0721 glutamine amidotransferase class-I. (240 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
 
 0.974
guaAB
GMP synthase (glutamine-hydrolyzing) subunit B; Catalyzes the synthesis of GMP from XMP.
 
  
 0.958
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
 
  
 0.937
AEN06698.1
PFAM: Phosphoribosyltransferase; KEGG: hbo:Hbor_28370 prpp-binding protein, adenine/guanine phosphoribosyltransferase.
 
 
 0.937
AEN06059.1
Phosphoribosyltransferase; May catalyze a purine salvage reaction, the substrate is unknown.
  
 
 0.927
AEN06109.1
Glutamine amidotransferase class-I; KEGG: hbo:Hbor_27060 GMP synthase family protein; manually curated; PFAM: Glutamine amidotransferase class-I, C-terminal.
  
  
 
0.919
guaAA
GMP synthase (glutamine-hydrolyzing) subunit A; Catalyzes the synthesis of GMP from XMP.
 
  
 
0.918
AEN06363.1
Nucleoside-triphosphatase; KEGG: hbo:Hbor_04980 ditpase; PFAM: Ham1-like protein.
  
 
 0.913
AEN05864.1
5'-Nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; KEGG: hbo:Hbor_11400 5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase.
    
 0.907
AEN06866.1
KEGG: hsl:OE4500R acyl-CoA dehydrogenase; PFAM: Acyl-CoA oxidase/dehydrogenase, type 1; Acyl-CoA dehydrogenase, N-terminal; Acyl-CoA oxidase/dehydrogenase, central region.
 
     0.674
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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