| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEN06045.1 | AEN06879.1 | Halar_2382 | Halar_3269 | Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: hvo:HVO_1666 phosphopantetheine adenylyltransferase; PFAM: Cytidylyltransferase. | Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | 0.799 |
| AEN06363.1 | AEN06879.1 | Halar_2720 | Halar_3269 | Nucleoside-triphosphatase; KEGG: hbo:Hbor_04980 ditpase; PFAM: Ham1-like protein. | Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | 0.908 |
| AEN06363.1 | ndk | Halar_2720 | Halar_2170 | Nucleoside-triphosphatase; KEGG: hbo:Hbor_04980 ditpase; PFAM: Ham1-like protein. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.936 |
| AEN06876.1 | AEN06878.1 | Halar_3266 | Halar_3268 | KEGG: hje:HacjB3_00260 hypothetical protein. | ABC-type transporter, periplasmic subunit; PFAM: Periplasmic binding protein; KEGG: hla:Hlac_0602 iron/cobalamin ABC transporter periplasmic substrate-binding protein. | 0.470 |
| AEN06876.1 | AEN06879.1 | Halar_3266 | Halar_3269 | KEGG: hje:HacjB3_00260 hypothetical protein. | Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | 0.434 |
| AEN06876.1 | aroD | Halar_3266 | Halar_3267 | KEGG: hje:HacjB3_00260 hypothetical protein. | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.648 |
| AEN06878.1 | AEN06876.1 | Halar_3268 | Halar_3266 | ABC-type transporter, periplasmic subunit; PFAM: Periplasmic binding protein; KEGG: hla:Hlac_0602 iron/cobalamin ABC transporter periplasmic substrate-binding protein. | KEGG: hje:HacjB3_00260 hypothetical protein. | 0.470 |
| AEN06878.1 | AEN06879.1 | Halar_3268 | Halar_3269 | ABC-type transporter, periplasmic subunit; PFAM: Periplasmic binding protein; KEGG: hla:Hlac_0602 iron/cobalamin ABC transporter periplasmic substrate-binding protein. | Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | 0.763 |
| AEN06878.1 | aroD | Halar_3268 | Halar_3267 | ABC-type transporter, periplasmic subunit; PFAM: Periplasmic binding protein; KEGG: hla:Hlac_0602 iron/cobalamin ABC transporter periplasmic substrate-binding protein. | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.568 |
| AEN06879.1 | AEN06045.1 | Halar_3269 | Halar_2382 | Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | Cytidyltransferase-related domain protein; TIGRFAM: Cytidyltransferase-related; KEGG: hvo:HVO_1666 phosphopantetheine adenylyltransferase; PFAM: Cytidylyltransferase. | 0.799 |
| AEN06879.1 | AEN06363.1 | Halar_3269 | Halar_2720 | Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | Nucleoside-triphosphatase; KEGG: hbo:Hbor_04980 ditpase; PFAM: Ham1-like protein. | 0.908 |
| AEN06879.1 | AEN06876.1 | Halar_3269 | Halar_3266 | Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | KEGG: hje:HacjB3_00260 hypothetical protein. | 0.434 |
| AEN06879.1 | AEN06878.1 | Halar_3269 | Halar_3268 | Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | ABC-type transporter, periplasmic subunit; PFAM: Periplasmic binding protein; KEGG: hla:Hlac_0602 iron/cobalamin ABC transporter periplasmic substrate-binding protein. | 0.763 |
| AEN06879.1 | aroD | Halar_3269 | Halar_3267 | Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.570 |
| AEN06879.1 | ileS | Halar_3269 | Halar_1449 | Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.442 |
| AEN06879.1 | ndk | Halar_3269 | Halar_2170 | Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.900 |
| aroD | AEN06876.1 | Halar_3267 | Halar_3266 | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | KEGG: hje:HacjB3_00260 hypothetical protein. | 0.648 |
| aroD | AEN06878.1 | Halar_3267 | Halar_3268 | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | ABC-type transporter, periplasmic subunit; PFAM: Periplasmic binding protein; KEGG: hla:Hlac_0602 iron/cobalamin ABC transporter periplasmic substrate-binding protein. | 0.568 |
| aroD | AEN06879.1 | Halar_3267 | Halar_3269 | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | 0.570 |
| ileS | AEN06879.1 | Halar_1449 | Halar_3269 | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | 0.442 |
