Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06895.1KEGG: hvo:HVO_0013 putative KEOPS complex component. (167 aa)    
Predicted Functional Partners:
AEN06365.1
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family.
    
 0.999
hel308
Ski2-type helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
       0.907
AEN04761.1
PFAM: Protein of unknown function DUF2144; KEGG: hla:Hlac_0566 rpo operon protein.
     
 0.860
AEN04692.1
PFAM: Amino acid-binding ACT; KEGG: nmg:Nmag_2514 amino acid-binding ACT domain protein.
  
     0.726
AEN07059.1
PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: hvo:HVO_0292 replication protein A.
  
     0.686
AEN06030.1
Flagellin domain protein; KEGG: hvo:HVO_2062 hypothetical protein; TIGRFAM: Archaeal flagellin, N-terminal related; PFAM: Protein of unknown function DUF1628.
  
     0.670
cofC
2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
     0.665
rpoL
DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
  
     0.653
AEN05541.1
PFAM: RNA polymerase II, Rpb4; KEGG: hje:HacjB3_08615 RNA polymerase RPB4.
  
     0.650
AEN06574.1
PFAM: Uncharacterised conserved protein UCP004977; KEGG: nmg:Nmag_1928 hypothetical protein.
  
     0.645
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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