Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06906.1TIGRFAM: 2-methylcitrate synthase/citrate synthase type I; KEGG: hla:Hlac_0723 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase-like. (384 aa)    
Predicted Functional Partners:
AEN05954.1
KEGG: hbo:Hbor_02300 malate dehydrogenase (NAD); PFAM: Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.999
AEN05617.1
KEGG: hma:rrnAC2158 aconitate hydratase; TIGRFAM: Aconitase, putative; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel.
  
 0.996
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.991
AEN06483.1
Dihydrolipoyllysine-residue acetyltransferase; KEGG: hla:Hlac_0141 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding.
  
 0.979
sucC
Succinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.979
AEN05093.1
KEGG: hla:Hlac_0706 NADH-ubiquinone oxidoreductase chain 49kDa; HAMAP: NAD(P)H-quinone oxidoreductase subunit H; PFAM: NADH-quinone oxidoreductase, subunit D; NADH:ubiquinone oxidoreductase, 30kDa subunit.
  
 0.963
AEN05594.1
KEGG: hbo:Hbor_11050 propionyl-CoA carboxylase carboxyltransferase subunit; PFAM: Carboxyl transferase.
  
 
 0.952
AEN04921.1
Propanoyl-CoA C-acyltransferase; KEGG: hbo:Hbor_22070 acetyl-CoA acetyltransferase.
  
 0.950
AEN07150.1
KEGG: hvo:HVO_A0522 acetyl-CoA C-acyltransferase; PFAM: Beta-ketoacyl synthase, N-terminal.
  
 0.950
AEN07200.1
Propanoyl-CoA C-acyltransferase; KEGG: hla:Hlac_1006 thiolase; PFAM: Beta-ketoacyl synthase, N-terminal.
  
 0.950
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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