Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEN06909.1KEGG: hut:Huta_1767 protein of unknown function DUF99; manually curated; PFAM: Protein of unknown function DUF99. (212 aa)    
Predicted Functional Partners:
AEN06910.1
KEGG: htu:Htur_3156 hypothetical protein.
       0.878
AEN06913.1
KEGG: hvo:HVO_0441 putative metallo-beta-lactamase family hydrolase.
       0.812
AEN06767.1
KEGG: hbo:Hbor_27510 uracil-DNA glycosylase, family 4; TIGRFAM: Phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase-like.
       0.730
AEN06908.1
KEGG: hvo:HVO_0468 hypothetical protein.
       0.615
AEN06911.1
Lactate utilization protein B/C; PFAM: Protein of unknown function DUF162; KEGG: htu:Htur_3880 protein of unknown function DUF162.
 
     0.576
AEN06912.1
Lactate utilization protein B/C; PFAM: Protein of unknown function DUF162; Cysteine-rich region, CCG; KEGG: hbo:Hbor_15190 hypothetical protein.
 
     0.573
AEN06019.1
PFAM: Type II secretion system F domain; KEGG: hbo:Hbor_20820 archaeal flagella assembly protein J.
  
     0.542
AEN04692.1
PFAM: Amino acid-binding ACT; KEGG: nmg:Nmag_2514 amino acid-binding ACT domain protein.
  
     0.522
AEN07266.1
KEGG: hvo:HVO_0422 hypothetical protein.
  
     0.519
pth
Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
 
     0.515
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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