Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06977.1PFAM: Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; KEGG: hvo:HVO_0076 uroporphyrinogen-III synthase. (247 aa)    
Predicted Functional Partners:
AEN06976.1
Porphobilinogen deaminase; TIGRFAM: Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; KEGG: hvo:HVO_0078 porphobilinogen deaminase; PFAM: Tetrapyrrole biosynthesis, hydroxymethylbilane synthase.
 
 0.999
AEN06974.1
Porphobilinogen synthase; KEGG: hmu:Hmuk_0925 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.975
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.939
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.824
hemL
HAMAP: Glutamate-1-semialdehyde 2,1-aminomutase; KEGG: htu:Htur_0185 aminotransferase class-III; PFAM: Aminotransferase class-III.
 
  
 0.732
AEN06384.1
TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Cation/H+ exchanger; Regulator of K+ conductance, C-terminal; KEGG: hbo:Hbor_05150 sodium/proton antiporter, cpa1 family.
  
  
 0.707
AEN05653.1
TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: hbo:Hbor_06490 k+ transporter, NAD-binding component.
  
    0.671
AEN06346.1
PFAM: Chlorite dismutase; Antibiotic biosynthesis monooxygenase; KEGG: hbo:Hbor_04740 hypothetical protein.
 
   
 0.564
AEN04737.1
PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; KEGG: hbo:Hbor_01460 single-stranded DNA-specific exonuclease.
 
     0.548
AEN05259.1
Radical SAM domain protein; KEGG: hbo:Hbor_34360 predicted Fe-S oxidoreductase; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB.
 
  
 0.469
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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