Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN06980.1PFAM: Cytidylyltransferase; TIGRFAM: Nicotinamide-nucleotide adenylyltransferase, archaeal type; Cytidyltransferase-related; HAMAP: Nicotinamide-nucleotide adenylyltransferase, archaeal type; KEGG: hla:Hlac_1037 nicotinamide-nucleotide adenylyltransferase. (170 aa)    
Predicted Functional Partners:
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
 
  
 0.955
AEN05629.1
PFAM: Quinolinate phosphoribosyl transferase; KEGG: hvo:HVO_1804 nicotinate phosphoribosyltransferase.
 
  
 0.942
AEN04556.1
CinA domain protein; KEGG: hbo:Hbor_24930 competence/damage-inducible protein CinA-like protein; TIGRFAM: CinA, C-terminal; PFAM: CinA, C-terminal.
    
 0.941
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.916
AEN07218.1
KEGG: hje:HacjB3_11085 ATP-NAD/AcoX kinase.
    
 0.916
AEN05864.1
5'-Nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; KEGG: hbo:Hbor_11400 5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase.
     
 0.902
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
AEN06981.1
SMART: ATPase, AAA+ type, core; TIGRFAM: Peptidase S16, archaeal lon homologues; KEGG: hwa:HQ1163A ATP-dependent protease Lon; PFAM: Peptidase S16, lon C-terminal; Magnesium chelatase, ChlI subunit; Belongs to the peptidase S16 family.
 
     0.865
AEN06982.1
PFAM: Abortive infection protein; KEGG: hje:HacjB3_14285 abortive infection protein.
       0.839
AEN06979.1
PFAM: Uncharacterised protein family UPF0126; KEGG: hje:HacjB3_14260 UPF0126 domain protein.
       0.795
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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