Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (923 aa)    
Predicted Functional Partners:
AEN05775.1
PFAM: Threonyl/alanyl tRNA synthetase, SAD; Alanyl-tRNA synthetase, class IIc, N-terminal; Phosphoesterase, DHHA1; KEGG: hvo:HVO_2717 alanyl-tRNA synthetase.
  
  
 
0.915
leuS
TIGRFAM: Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic; KEGG: hbo:Hbor_27430 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.823
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
 
 0.817
AEN07243.1
Acylaminoacyl-peptidase; KEGG: gct:GC56T3_2594 peptidase S9 prolyl oligopeptidase active site domain protein.
  
 0.759
trpS
Tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp).
 
 
 0.751
htpX
Protease htpX; KEGG: hwa:HQ3431A heat shock protein HtpX; HAMAP: protease htpX; PFAM: Peptidase M48, Ste24p; Belongs to the peptidase M48B family.
  
    0.750
AEN05324.1
PFAM: Peptidase M48, Ste24p; KEGG: hmu:Hmuk_0373 peptidase M48 Ste24p.
  
    0.750
secD
Preprotein translocase subunit SecD; Involved in protein export.
 
  
 0.745
AEN04728.1
PFAM: Tetratricopeptide TPR-1; KEGG: hbo:Hbor_01120 tetratricopeptide hypothetical protein.
   
 0.734
valS
Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
  
  
 0.721
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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