Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN07055.1TIGRFAM: DNA-binding protein Tfx, archaea; KEGG: hbo:Hbor_28760 DNA-binding protein, tfx family. (169 aa)    
Predicted Functional Partners:
AEN07054.1
PFAM: Deoxyribonuclease/rho motif-related TRAM; KEGG: hla:Hlac_2542 deoxyribonuclease/rho motif-related TRAM.
       0.868
AEN07053.1
KEGG: hla:Hlac_2541 hypothetical protein.
 
     0.804
AEN04692.1
PFAM: Amino acid-binding ACT; KEGG: nmg:Nmag_2514 amino acid-binding ACT domain protein.
  
     0.694
AEN05358.1
PFAM: Major facilitator superfamily MFS-1; KEGG: nmg:Nmag_3958 major facilitator superfamily MFS_1.
  
     0.620
AEN06019.1
PFAM: Type II secretion system F domain; KEGG: hbo:Hbor_20820 archaeal flagella assembly protein J.
  
     0.598
AEN05417.1
Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain protein; PFAM: Protein of unknown function DUF293, archaea; KEGG: hbo:Hbor_16490 transcriptional regulator, contains C-terminal cbs domains.
  
    0.537
AEN05564.1
PFAM: Protein of unknown function DUF63; KEGG: hwa:HQ2794A hypothetical protein.
  
     0.530
cofC
2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
     0.527
AEN05483.1
PFAM: Triphosphoribosyl-dephospho-CoA protein; KEGG: hla:Hlac_2336 triphosphoribosyl-dephospho-CoA protein.
  
     0.509
AEN07286.1
KEGG: hla:Hlac_1854 GCN5-related N-acetyltransferase.
  
     0.483
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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