Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mptDProtein of unknown function DUF372; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. (115 aa)    
Predicted Functional Partners:
mptE
Protein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family.
 
  
 0.984
AEN04575.1
TIGRFAM: Dihydropteroate synthase; Folylpolyglutamate synthetase; KEGG: hje:HacjB3_13760 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; Mur ligase, C-terminal; Mur ligase, central.
    
 0.927
AEN07079.1
KEGG: hla:Hlac_0081 hypothetical protein.
       0.841
AEN07077.1
NAD-dependent epimerase/dehydratase; Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
       0.809
AEN05448.1
UPF0179 protein; KEGG: hvo:HVO_2851 hypothetical protein; HAMAP: UPF0179 protein; PFAM: Uncharacterised protein family UPF0179; Belongs to the UPF0179 family.
  
     0.730
mptA
Protein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
 
   
 0.721
AEN06694.1
Transcriptional regulator, XRE family; HAMAP: HTH-type transcriptional regulatory protein; PFAM: Helix-turn-helix type 3; KEGG: hbo:Hbor_28330 transcriptional regulator, xre family; SMART: Helix-turn-helix type 3.
  
     0.697
AEN05910.1
TIGRFAM: Conserved hypothetical protein CHP01210; PFAM: Radical SAM; KEGG: hma:rrnAC3263 hypothetical protein; SMART: Elongator protein 3/MiaB/NifB.
  
     0.687
AEN06168.1
Hypothetical protein; Manually curated; KEGG: hut:Huta_0046 hypothetical protein.
  
     0.680
AEN04628.1
KEGG: hla:Hlac_0452 hypothetical protein.
  
     0.671
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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