Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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Textmining
[Homology]
Score
AEN07089.1SMART: Rhodanese-like; KEGG: hje:HacjB3_02970 fused rhodanese domain-containing protein/hydrolase. (383 aa)    
Predicted Functional Partners:
AEN07091.1
PFAM: Protein of unknown function DUF395, YeeE/YedE; KEGG: hje:HacjB3_02960 hypothetical protein.
 
    0.879
AEN07090.1
PFAM: Protein of unknown function DUF395, YeeE/YedE; KEGG: hje:HacjB3_02965 YeeE/YedE family protein family.
  
    0.862
AEN07088.1
PFAM: SirA-like; KEGG: hbo:Hbor_34670 predicted redox protein, regulator of disulfide bond formation.
 
 
 0.844
AEN07087.1
KEGG: hmu:Hmuk_3384 hypothetical protein.
 
  
 0.768
AEN04719.1
TIGRFAM: Cysteine desulfurase, SufS; KEGG: hbo:Hbor_34450 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; NIF system FeS cluster assembly, NifU, N-terminal.
  
 
 0.607
rps17
Ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
 
  0.574
AEN06913.1
KEGG: hvo:HVO_0441 putative metallo-beta-lactamase family hydrolase.
 
 
 0.529
rpl13
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
 
   0.498
AEN07086.1
PFAM: Protein of unknown function DUF302; KEGG: hma:pNG6027 hypothetical protein.
 
     0.496
AEN05112.1
PFAM: Protein of unknown function DUF395, YeeE/YedE; KEGG: hla:Hlac_1499 protein of unknown function DUF395 YeeE/YedE.
 
    0.490
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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