Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN07105.1PFAM: NUDIX hydrolase domain; KEGG: hvo:HVO_1051 Mut/NUDIX family protein. (156 aa)    
Predicted Functional Partners:
flpA
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.622
AEN07104.1
Hypothetical protein.
       0.548
AEN07238.1
PFAM: GCN5-related N-acetyltransferase; KEGG: hbo:Hbor_09040 acetyltransferase (GNAT) family protein.
 
     0.487
AEN04677.1
PFAM: Ribonuclease II/R; KEGG: hla:Hlac_0359 ribonuclease II.
  
 0.469
AEN07103.1
KEGG: hwa:HQ2350A hypothetical protein.
       0.460
AEN05939.1
KEGG: hla:Hlac_2163 hypothetical protein.
 
     0.456
fau-1
RNA-binding protein AU-1; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.
 
   
 0.430
AEN04776.1
SMART: Helicase, ATP-dependent, c2 type; KEGG: hvo:HVO_0099 hypothetical protein.
 
    0.417
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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