Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN07111.1DEAD/H associated domain protein; KEGG: hvo:HVO_1333 ATP-dependent DNA helicase; PFAM: DEAD/H associated; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal. (950 aa)    
Predicted Functional Partners:
AEN05191.1
PFAM: Metallophosphoesterase; KEGG: hbo:Hbor_18990 phosphoesterase.
 
    0.769
AEN05189.1
PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: hla:Hlac_0623 replication factor A.
 
   
 0.610
AEN07255.1
KEGG: hla:Hlac_1971 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3.
  
     0.607
AEN06643.1
PFAM: Protein of unknown function DUF373; KEGG: hvo:HVO_0302 hypothetical protein.
  
     0.606
AEN04626.1
PFAM: Protein of unknown function DUF373; KEGG: hvo:HVO_0882 hypothetical protein.
  
     0.599
AEN05190.1
KEGG: hla:Hlac_0624 hypothetical protein.
 
     0.565
ribK
Riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.542
AEN07112.1
TIGRFAM: Amidase, hydantoinase/carbamoylase; KEGG: hla:Hlac_1507 amidase, hydantoinase/carbamoylase family; PFAM: Peptidase M20; Peptidase M20, dimerisation.
       0.536
dtdA
D-tyrosyl-tRNA(Tyr) deacylase; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
 
 
   0.505
lig
DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 
    0.497
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (12%) [HD]