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query proteins and first shell of interactors
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second shell of interactors
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a 3D structure is known or predicted
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aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (386 aa)    
Predicted Functional Partners:
aroA-2
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 
 0.999
AEN06184.1
Chorismate mutase, type II; KEGG: htu:Htur_5134 chorismate mutase; manually curated; PFAM: Chorismate mutase, type II.
 
 
 0.979
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
 0.965
AEN05810.1
TIGRFAM: Glutamine amidotransferase of anthranilate synthase; KEGG: hmu:Hmuk_1768 glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I, C-terminal.
 
 
 0.956
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
 
 0.954
AEN05063.1
TIGRFAM: Para-aminobenzoate synthase/anthranilate synthase, component I; KEGG: htu:Htur_1366 para-aminobenzoate synthase component I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal.
 
 
 0.953
AEN05062.1
TIGRFAM: Glutamine amidotransferase of anthranilate synthase; KEGG: hbo:Hbor_25070 aminodeoxychorismate synthase, glutamine amidotransferase subunit; PFAM: Glutamine amidotransferase class-I, C-terminal.
 
 
 0.952
AEN05233.1
TIGRFAM: Isochorismate synthase; KEGG: hje:HacjB3_08360 isochorismate synthase; PFAM: Chorismate binding, C-terminal.
 
  
 0.881
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
  
 0.840
aroD
3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
 
  
 0.811
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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