STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Cooccurrence
Coexpression
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[Homology]
Score
matS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (404 aa)    
Predicted Functional Partners:
metE
Methylcobalamin:homocysteine methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown.
  
  
  0.911
AEN06158.1
KEGG: hmu:Hmuk_2306 methionine adenosyltransferase; PFAM: S-adenosylmethionine synthetase (MAT), archaea.
  
  
 
0.906
AEN05241.1
Cysteine synthase; KEGG: hbo:Hbor_02440 oah/oas sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme.
     
  0.900
AEN05846.1
Cobalamin-independent synthase MetE domain protein; PFAM: Cobalamin (vitamin B12)-independent methionine synthase MetE, N-terminal; KEGG: hvo:HVO_2743 methionine synthase vitamin-B12 independent.
     
  0.900
thiI
tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
     0.794
AEN07134.1
PFAM: Peptidyl-prolyl cis-trans isomerase, FKBP-type; KEGG: hla:Hlac_0806 peptidylprolyl isomerase FKBP-type.
 
  
 0.750
AEN07139.1
KEGG: nph:NP3102A hypothetical protein.
       0.657
AEN07137.1
PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; KEGG: hmu:Hmuk_2384 protein of unknown function DUF21.
       0.562
AEN07135.1
KEGG: hma:rrnAC2117 hypothetical protein.
       0.561
AEN07255.1
KEGG: hla:Hlac_1971 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3.
 
     0.481
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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