STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiItRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (393 aa)    
Predicted Functional Partners:
AEN05313.1
TIGRFAM: Nop2p; KEGG: hbo:Hbor_16210 nol1/nop2/sun family RNA methylase; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
    0.875
AEN07139.1
KEGG: nph:NP3102A hypothetical protein.
       0.669
AEN04825.1
TIGRFAM: Phosphomethylpyrimidine kinase type-2; KEGG: hla:Hlac_2988 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; Phosphomethylpyrimidine kinase.
     
 0.585
AEN06401.1
TIGRFAM: MiaB-like tRNA modifying enzyme, archaeal-type; Methylthiotransferase; PFAM: Radical SAM; Methylthiotransferase, N-terminal; KEGG: hvo:HVO_2605 MiaB-like tRNA modifying enzyme, archaeal-type; SMART: Elongator protein 3/MiaB/NifB.
  
  
 0.580
AEN07137.1
PFAM: Protein of unknown function DUF21; Cystathionine beta-synthase, core; KEGG: hmu:Hmuk_2384 protein of unknown function DUF21.
     
 0.555
mat
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family.
 
     0.545
thrS
KEGG: hla:Hlac_1764 threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved region; Threonyl/alanyl tRNA synthetase, SAD; TGS; Anticodon-binding; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.531
AEN05915.1
MoaD family protein; KEGG: hma:rrnAC2057 molybdopterin converting factor subunit 1; TIGRFAM: MoaD, archaeal; PFAM: ThiamineS.
   
  
 0.527
AEN04719.1
TIGRFAM: Cysteine desulfurase, SufS; KEGG: hbo:Hbor_34450 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; NIF system FeS cluster assembly, NifU, N-terminal.
     
 0.523
AEN06530.1
Protein of unknown function UPF0021; KEGG: hvo:HVO_0580 N-type ATP pyrophosphatase superfamily protein; TIGRFAM: Uncharacterised protein family UPF0021, C-terminal; PFAM: PP-loop.
  
  
 0.500
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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