Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
thiItRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (393 aa)    
Predicted Functional Partners:
AEN06530.1
Protein of unknown function UPF0021; KEGG: hvo:HVO_0580 N-type ATP pyrophosphatase superfamily protein; TIGRFAM: Uncharacterised protein family UPF0021, C-terminal; PFAM: PP-loop.
  
 
 0.901
AEN04719.1
TIGRFAM: Cysteine desulfurase, SufS; KEGG: hbo:Hbor_34450 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; NIF system FeS cluster assembly, NifU, N-terminal.
    
 0.840
AEN07139.1
KEGG: nph:NP3102A hypothetical protein.
       0.830
mat
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family.
 
     0.794
AEN06528.1
PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: hla:Hlac_0421 UBA/ThiF-type NAD/FAD binding protein.
    
 0.692
AEN06628.1
PFAM: ThiamineS; KEGG: hvo:HVO_0202 hypothetical protein.
     
 0.605
AEN04731.1
KEGG: hla:Hlac_2247 SUF system FeS assembly protein, NifU family; TIGRFAM: SUF system FeS cluster assembly, SufU scaffold; PFAM: NIF system FeS cluster assembly, NifU, N-terminal.
    
 0.600
AEN05313.1
TIGRFAM: Nop2p; KEGG: hbo:Hbor_16210 nol1/nop2/sun family RNA methylase; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
    0.576
tiaS
Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
   
 0.575
AEN05915.1
MoaD family protein; KEGG: hma:rrnAC2057 molybdopterin converting factor subunit 1; TIGRFAM: MoaD, archaeal; PFAM: ThiamineS.
   
 
 0.569
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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