Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN07141.1Thioredoxin; KEGG: hbo:Hbor_15610 thioredoxin. (130 aa)    
Predicted Functional Partners:
AEN07140.1
Cysteine synthase; KEGG: hmu:Hmuk_2310 pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit.
   
 
 0.804
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 0.779
AEN05667.1
KEGG: nph:NP3056A peptidylprolyl isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type.
   
 0.746
AEN06167.1
KEGG: hvo:HVO_1134 hypothetical protein.
  
     0.715
msrA
Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.700
AEN05492.1
PFAM: Protein of unknown function DUF87; KEGG: hbo:Hbor_07980 ATPase.
 
     0.655
AEN06012.1
Heat shock protein DnaJ domain protein; KEGG: hbo:Hbor_22210 DnaJ-class molecular chaperone with C-terminal zn finger domain; PFAM: Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal.
   
 0.621
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 0.621
AEN04741.1
PFAM: Major facilitator superfamily MFS-1; KEGG: hla:Hlac_1455 major facilitator superfamily MFS_1.
  
 
   0.620
AEN04933.1
PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFTu/EF1A, C-terminal; KEGG: hut:Huta_1155 protein synthesis factor GTP-binding.
 
 
 0.578
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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