Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN07149.1PFAM: Protein of unknown function DUF35; KEGG: nph:NP2608A hydroxymethylglutaryl-CoA synthase 1. (469 aa)    
Predicted Functional Partners:
AEN04921.1
Propanoyl-CoA C-acyltransferase; KEGG: hbo:Hbor_22070 acetyl-CoA acetyltransferase.
 
 0.999
AEN06381.1
KEGG: hla:Hlac_1850 acetyl-CoA acetyltransferase; TIGRFAM: Thiolase.
  
 0.999
AEN07150.1
KEGG: hvo:HVO_A0522 acetyl-CoA C-acyltransferase; PFAM: Beta-ketoacyl synthase, N-terminal.
 
 0.999
AEN07200.1
Propanoyl-CoA C-acyltransferase; KEGG: hla:Hlac_1006 thiolase; PFAM: Beta-ketoacyl synthase, N-terminal.
 
 0.999
AEN06468.1
TIGRFAM: Hydroxymethylglutaryl-CoA reductase, class I, catalytic; KEGG: hvo:HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH); PFAM: Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic; Belongs to the HMG-CoA reductase family.
 
 
 0.997
AEN07279.1
KEGG: hbo:Hbor_08530 hydroxymethylglutaryl-CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase, N-terminal; Hydroxymethylglutaryl-coenzyme A synthase C-terminal.
  
 0.993
AEN07255.1
KEGG: hla:Hlac_1971 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3.
  
    0.987
AEN07148.1
KEGG: hbo:Hbor_36430 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal.
    
  0.953
AEN04524.1
KEGG: hbo:Hbor_17950 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; 3-hydroxyacyl-CoA dehydrogenase, C-terminal.
    
  0.918
AEN04621.1
TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: htu:Htur_1985 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
    
 0.901
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (18%) [HD]