Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN07283.1PFAM: Deoxyribonuclease, TatD-related; KEGG: hbo:Hbor_08490 metal-dependent hydrolase (urease superfamily). (284 aa)    
Predicted Functional Partners:
AEN07282.1
PFAM: Uncharacterised conserved protein UCP022079; KEGG: hla:Hlac_1933 hypothetical protein.
 
     0.899
AEN07254.1
PFAM: Protein of unknown function DUF88; KEGG: hla:Hlac_1242 protein of unknown function DUF88.
 
     0.766
rpl40e
KEGG: hut:Huta_1320 50S ribosomal protein L40e; HAMAP: 50S ribosomal protein L40e; PFAM: Ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
 
     0.738
AEN04779.1
NMD3 family protein; PFAM: NMD3; KEGG: hbo:Hbor_01210 nmd protein affecting ribosome stability and mRNA decay.
 
     0.732
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
 
     0.689
AEN05448.1
UPF0179 protein; KEGG: hvo:HVO_2851 hypothetical protein; HAMAP: UPF0179 protein; PFAM: Uncharacterised protein family UPF0179; Belongs to the UPF0179 family.
  
     0.681
AEN05910.1
TIGRFAM: Conserved hypothetical protein CHP01210; PFAM: Radical SAM; KEGG: hma:rrnAC3263 hypothetical protein; SMART: Elongator protein 3/MiaB/NifB.
  
     0.673
AEN05690.1
PUA domain containing protein; KEGG: hbo:Hbor_06070 tRNA-archaeosine synthase; PFAM: Pseudouridine synthase/archaeosine transglycosylase; Queuine/other tRNA-ribosyltransferase; SMART: Pseudouridine synthase/archaeosine transglycosylase.
  
     0.661
AEN07255.1
KEGG: hla:Hlac_1971 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3.
  
     0.636
mptD
Protein of unknown function DUF372; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
 
     0.612
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
Server load: low (8%) [HD]