Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN07300.1PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: hbo:Hbor_26610 2-keto-3-deoxygluconate kinase. (323 aa)    
Predicted Functional Partners:
AEN07299.1
Chloromuconate cycloisomerase; KEGG: hvo:HVO_1488 mandelate racemase/muconate lactonizing enzyme family protein; PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal; Mandelate racemase/muconate lactonizing enzyme, C-terminal.
 
  
 0.982
AEN04775.1
Galactonate dehydratase; KEGG: nmg:Nmag_0821 mandelate racemase/muconate lactonizing protein; PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal; Mandelate racemase/muconate lactonizing enzyme, N-terminal.
 
  
 0.926
AEN04785.1
PfkB domain protein; PFAM: Carbohydrate/purine kinase; KEGG: hla:Hlac_0463 PfkB domain protein.
  
  
 
0.907
mutL
DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
  
 0.747
hisA
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; HAMAP: 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; KEGG: hla:Hlac_2699 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
  
    0.631
AEN05365.1
Manganese/iron superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.601
rfcL
Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily.
  
    0.597
AEN07100.1
KEGG: htu:Htur_0531 oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal.
 
  
 0.517
AEN04698.1
PFAM: Class II aldolase/adducin, N-terminal; KEGG: htu:Htur_2784 class II aldolase/adducin family protein.
 
  
 0.450
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.445
Your Current Organism:
halophilic archaeon DL31
NCBI taxonomy Id: 756883
Other names: h. archaeon DL31
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