STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106168850G2/mitotic-specific cyclin-A-like; Belongs to the cyclin family. (424 aa)    
Predicted Functional Partners:
LOC106155022
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.978
LOC106177726
Ubiquitin-conjugating enzyme E2 C-like; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.953
LOC106177747
DNA replication factor Cdt1-like isoform X1.
   
 0.951
LOC106171246
S-phase kinase-associated protein 2 isoform X1.
   
 0.948
LOC106168564
Anaphase-promoting complex subunit 4-like.
    
 0.935
LOC106181029
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.919
LOC106181039
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
 0.917
LOC106161413
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
 
 
 
 0.915
LOC106152763
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.906
LOC106161157
Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily.
   
 0.906
Your Current Organism:
Lingula anatina
NCBI taxonomy Id: 7574
Other names: L. anatina, Lingula lingua, Lingula unguis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.