STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106173628Leucine-rich repeat protein 1. (425 aa)    
Predicted Functional Partners:
LOC106151911
Cullin-2; Belongs to the cullin family.
    
 0.983
LOC106150763
RING-box protein 1.
    
 0.982
LOC106165645
elongin-C; Belongs to the SKP1 family.
    
 0.982
LOC106181977
elongin-B.
    
 0.978
LOC106161413
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.881
LOC106173359
DNA helicase; Belongs to the MCM family.
   
 
 0.820
LOC106157709
WD repeat and HMG-box DNA-binding protein 1-like.
   
 
 0.758
LOC106166150
Claspin.
   
 
 0.758
LOC106173301
WD repeat and HMG-box DNA-binding protein 1.
   
 
 0.758
LOC106167595
DNA replication complex GINS protein PSF1-like.
   
   0.737
Your Current Organism:
Lingula anatina
NCBI taxonomy Id: 7574
Other names: L. anatina, Lingula lingua, Lingula unguis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.