STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106173811N-lysine methyltransferase KMT5A-A. (346 aa)    
Predicted Functional Partners:
LOC106177733
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.935
LOC106155691
Calmodulin-lysine N-methyltransferase isoform X1.
     
 0.918
LOC106160356
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 isoform X1.
    
  0.903
LOC106173736
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
   0.852
LOC106164488
Cellular tumor antigen p53 isoform X1.
   
 0.701
LOC106164989
Retinoblastoma-binding protein 5 homolog.
    
 0.691
LOC106177813
Uncharacterized protein LOC106177813.
    
 0.691
LOC106181502
Protein dpy-30 homolog.
    
 
 0.669
LOC106154540
set1/Ash2 histone methyltransferase complex subunit ASH2.
    
 0.649
LOC106177035
Histone H2A; Belongs to the histone H2A family.
   
 0.606
Your Current Organism:
Lingula anatina
NCBI taxonomy Id: 7574
Other names: L. anatina, Lingula lingua, Lingula unguis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.