STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106176633Uncharacterized protein LOC106176633. (1724 aa)    
Predicted Functional Partners:
LOC106151014
Fanconi anemia group M protein.
    
 0.984
LOC106179103
Ankyrin repeat domain-containing protein 6-like.
   
 0.948
LOC106151755
Werner syndrome ATP-dependent helicase isoform X1.
   
 0.891
LOC106176166
Werner syndrome ATP-dependent helicase homolog.
   
 0.891
LOC106179740
Werner syndrome ATP-dependent helicase homolog isoform X1.
   
 0.891
LOC106176905
DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.
   
 0.866
LOC106168825
DNA repair protein complementing XP-A cells homolog isoform X1.
    
 0.825
LOC106174949
DNA excision repair protein ERCC-1-like.
   
 0.822
LOC106178006
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.817
LOC106171898
E3 ubiquitin-protein ligase FANCL.
    
 0.785
Your Current Organism:
Lingula anatina
NCBI taxonomy Id: 7574
Other names: L. anatina, Lingula lingua, Lingula unguis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.