STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106177456Probable E3 ubiquitin-protein ligase HERC1. (643 aa)    
Predicted Functional Partners:
LOC106177464
Probable E3 ubiquitin-protein ligase HERC1 isoform X2.
 
    
0.921
LOC106154985
E3 SUMO-protein ligase PIAS2 isoform X1.
    
  0.524
LOC106152458
ubiquitin-40S ribosomal protein S27a.
    
 0.494
LOC106177733
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.480
LOC106164356
LOW QUALITY PROTEIN: AN1-type zinc finger protein 4-like.
    
 0.473
LOC106179761
Neuralized-like protein 4.
    
 
 0.457
LOC106164042
Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.456
LOC106152459
E3 ubiquitin-protein ligase RNF8-like.
   
 0.444
LOC106176674
E3 ubiquitin-protein ligase RNF8.
   
 0.444
LOC106159912
E3 ubiquitin-protein ligase RNF8-like.
   
 0.444
Your Current Organism:
Lingula anatina
NCBI taxonomy Id: 7574
Other names: L. anatina, Lingula lingua, Lingula unguis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.