STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sodBSuperoxide dismutase [Fe] protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (192 aa)    
Predicted Functional Partners:
rplQ
50S ribosomal subunit L17 protein.
   
   0.938
rpsQ
30S ribosomal subunit S17 protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
 
 0.929
rplO
50S ribosomal subunit L15 protein; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
 
 0.925
rplM
50S ribosomal subunit L13 protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.925
rplC
50S ribosomal subunit L3 protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
 
 0.919
dnaJ
Molecular chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between Dn [...]
  
 
 0.900
ybeY
Metal-dependent hydrolase protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
 
 0.887
btuE
Glutathione peroxidase protein; Belongs to the glutathione peroxidase family.
   
 0.856
rplK
50s ribosomal subunit L11 protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
   0.855
rplN
50S ribosomal subunit L14 protein; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.850
Your Current Organism:
Herbaspirillum seropedicae
NCBI taxonomy Id: 757424
Other names: H. seropedicae SmR1, Herbaspirillum seropedicae SmR1, Herbaspirillum seropedicae str. SmR1, Herbaspirillum seropedicae strain SmR1
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