STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADJ63777.1ATP-dependent DNA ligase protein. (555 aa)    
Predicted Functional Partners:
ADJ63778.1
Exonuclease of the beta-lactamase fold involved in RNA processing protein.
 0.990
ADJ63775.1
Calcineurin-like phosphoesterase protein.
 
   
 0.960
ADJ63776.1
ATP-dependent helicase superfamily II protein.
 
    0.955
lig
NAD-dependent DNA ligase (contains BRCT domain type II) protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
    
 0.920
polA
DNA polymerase I protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.911
dnaN
DNA polymerase III subunit beta protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...]
   
 0.902
ADJ63882.1
DNA polymerase IV protein.
  
 0.832
polB
DNA polymerase II protein.
   
 0.699
holB
DNA polymerase III delta subunit protein.
   
 0.672
ADJ62817.1
SMC domain protein.
   
 0.643
Your Current Organism:
Herbaspirillum seropedicae
NCBI taxonomy Id: 757424
Other names: H. seropedicae SmR1, Herbaspirillum seropedicae SmR1, Herbaspirillum seropedicae str. SmR1, Herbaspirillum seropedicae strain SmR1
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