STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
scyTo_0012799Uncharacterized protein. (232 aa)    
Predicted Functional Partners:
scyTo_0002388
RING-type domain-containing protein.
 
      0.899
scyTo_0011652
Uncharacterized protein.
    
  0.471
scyTo_0000656
Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
    
  0.471
scyTo_0019724
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
  0.471
scyTo_0006031
Uncharacterized protein.
      
 0.465
scyTo_0006463
Uncharacterized protein.
    
   0.445
scyTo_0013454
Uncharacterized protein.
     
 0.433
scyTo_0027962
STI1 domain-containing protein.
     
 0.433
scyTo_0010619
Uncharacterized protein.
   
   0.405
scyTo_0026304
Uncharacterized protein.
   
   0.405
Your Current Organism:
Scyliorhinus torazame
NCBI taxonomy Id: 75743
Other names: S. torazame, cloudy catshark
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.