STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
scyTo_0001542HMG box domain-containing protein. (501 aa)    
Predicted Functional Partners:
scyTo_0012116
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
   
 0.908
scyTo_0002871
PHD-type domain-containing protein.
    
 0.890
scyTo_0020299
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.848
scyTo_0011686
Uncharacterized protein.
    
 0.834
scyTo_0001770
HMG box domain-containing protein.
    
 
0.833
scyTo_0021689
Uncharacterized protein.
    
 0.827
scyTo_0003642
Uncharacterized protein.
   
 
 0.816
scyTo_0007114
DUF3736 domain-containing protein.
   
 0.815
scyTo_0000033
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
    
 0.790
scyTo_0006922
Uncharacterized protein; Belongs to the actin family.
    
 0.785
Your Current Organism:
Scyliorhinus torazame
NCBI taxonomy Id: 75743
Other names: S. torazame, cloudy catshark
Server load: low (16%) [HD]