STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
scyTo_0019071Reverse transcriptase domain-containing protein. (321 aa)    
Predicted Functional Partners:
scyTo_0002566
ERCC4 domain-containing protein.
    
 0.930
scyTo_0018644
Helicase C-terminal domain-containing protein.
    
 0.930
scyTo_0018666
Helicase ATP-binding domain-containing protein.
    
 0.930
scyTo_0007537
Uncharacterized protein.
   
 
 0.793
scyTo_0015963
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.772
scyTo_0010333
Uncharacterized protein.
    
 0.747
scyTo_0012980
CRC domain-containing protein.
    
 0.739
scyTo_0010573
RPA_C domain-containing protein.
   
 0.731
scyTo_0022682
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
   
 0.731
scyTo_0011670
DIRP domain-containing protein.
    
 0.730
Your Current Organism:
Scyliorhinus torazame
NCBI taxonomy Id: 75743
Other names: S. torazame, cloudy catshark
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.