STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHK41508.1Polyphosphate glucokinase. (258 aa)    
Predicted Functional Partners:
nadK
NAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.769
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
     
 0.769
SHK61179.1
Exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase.
     
 0.658
pfp
Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.650
SHK93870.1
PTS system, N-acetylglucosamine-specific IIC component.
    
   0.615
SHK93938.1
PTS system, N-acetylglucosamine-specific IIB component.
    
   0.615
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
 
   
 0.586
SHK08492.1
Glycogen operon protein; Belongs to the glycosyl hydrolase 13 family.
     
 0.585
SHK07372.1
Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain.
  
   
 0.564
SHK26588.1
Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain.
  
   
 0.524
Your Current Organism:
Nocardiopsis flavescens
NCBI taxonomy Id: 758803
Other names: CGMCC 4.5723, JCM 17424, N. flavescens, Nocardiopsis flavescens Fang et al. 2011, Nocardiopsis sp. SA6, strain SA6
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