SFM34763.1 protein (Rugamonas rubra) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

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Score

SFM34763.1

Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (291 aa)

Predicted Functional Partners:

SFL65979.1

0.755

SFM23414.1

0.748

SFL96782.1

0.732

SFM34652.1

0.724

SFM12806.1

0.717

SFL95735.1

0.716

SFL96704.1

0.704

SFM35225.1

0.699

SFM13969.1

0.690

SFM36567.1

0.689

Your Current Organism:

Rugamonas rubra

NCBI taxonomy Id: 758825
Other names: ATCC 43154, CCM 3730, R. rubra, strain MOM 28/2/79

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFL65979.1	SFM12806.1	SAMN02982985_01010	SAMN02982985_02830	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.656
SFL65979.1	SFM34763.1	SAMN02982985_01010	SAMN02982985_03731	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.755
SFL65979.1	SFM35225.1	SAMN02982985_01010	SAMN02982985_03759	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.672
SFL65979.1	SFM36567.1	SAMN02982985_01010	SAMN02982985_03828	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.614
SFL95735.1	SFM12806.1	SAMN02982985_02109	SAMN02982985_02830	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.598
SFL95735.1	SFM34652.1	SAMN02982985_02109	SAMN02982985_03725	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.455
SFL95735.1	SFM34763.1	SAMN02982985_02109	SAMN02982985_03731	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.716
SFL95735.1	SFM35225.1	SAMN02982985_02109	SAMN02982985_03759	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.751
SFL95735.1	SFM36567.1	SAMN02982985_02109	SAMN02982985_03828	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.544
SFL96704.1	SFL96782.1	SAMN02982985_02160	SAMN02982985_02165	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.765
SFL96704.1	SFM12806.1	SAMN02982985_02160	SAMN02982985_02830	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.659
SFL96704.1	SFM13969.1	SAMN02982985_02160	SAMN02982985_02905	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.442
SFL96704.1	SFM34652.1	SAMN02982985_02160	SAMN02982985_03725	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.534
SFL96704.1	SFM34763.1	SAMN02982985_02160	SAMN02982985_03731	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.704
SFL96704.1	SFM35225.1	SAMN02982985_02160	SAMN02982985_03759	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.672
SFL96782.1	SFL96704.1	SAMN02982985_02165	SAMN02982985_02160	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.765
SFL96782.1	SFM12806.1	SAMN02982985_02165	SAMN02982985_02830	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.674
SFL96782.1	SFM13969.1	SAMN02982985_02165	SAMN02982985_02905	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.596
SFL96782.1	SFM23414.1	SAMN02982985_02165	SAMN02982985_03296	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.754
SFL96782.1	SFM34763.1	SAMN02982985_02165	SAMN02982985_03731	DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.	0.732

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

36

PPI enrichment p-value:

0.000885

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000160

Phosphorelay signal transduction system

11 of 92

1.71

4.3

4.83e-16

GO:0018106

Peptidyl-histidine phosphorylation

3 of 31

1.61

1.09

0.0050

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000155

Phosphorelay sensor kinase activity

10 of 51

1.92

5.32

5.86e-16

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016021

Integral component of membrane

10 of 1095

0.59

0.48

0.00065

GO:0005886

Plasma membrane

8 of 841

0.61

0.45

0.0054

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3961

Phosphorelay sensor kinase activity

7 of 17

2.24

5.47

1.03e-12

CL:3959

Phosphorelay sensor kinase activity, and PAS domain

8 of 28

2.09

5.34

1.31e-13

CL:3945

Protein histidine kinase activity, and Diguanylate cyclase

9 of 54

1.85

4.51

1.30e-13

CL:3926

Signaling, and Diguanylate cyclase

11 of 142

1.52

3.21

3.34e-14

CL:3962

Phosphorelay sensor kinase activity, and Taxis

4 of 12

2.15

2.86

1.51e-06

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02020

Two-component system

11 of 396

1.07

1.46

2.42e-10

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0597

Phosphoprotein

8 of 72

1.67

3.24

1.85e-10

KW-0175

Coiled coil

8 of 484

0.85

0.76

0.00020

KW-0418

Kinase

4 of 123

1.14

0.74

0.0113

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00388

His Kinase A (phosphoacceptor) domain

9 of 33

2.06

5.88

1.02e-15

SM00387

Histidine kinase-like ATPases

9 of 40

1.98

5.44

2.35e-15

SM00448

cheY-homologous receiver domain

9 of 49

1.89

4.94

8.09e-15

SM00086

Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)

3 of 13

1.99

1.87

0.00017

SM00091

PAS domain

3 of 21

1.78

1.57

0.00048

(more ...)

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