STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyaYCyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (111 aa)    
Predicted Functional Partners:
SFM43500.1
FeS assembly scaffold apoprotein IscU /Modular FeS cluster scaffolding protein NifU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 
 0.996
SFM38551.1
Nitrogen fixation protein NifQ.
    
 0.991
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 0.990
SFM82913.1
Cysteine sulfinate desulfinase/cysteine desulfurase.
   
 0.989
SFM46332.1
Selenocysteine lyase/Cysteine desulfurase.
   
 0.987
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
 0.949
SFM43590.1
Ferredoxin, 2Fe-2S.
  
 
 0.929
hscB
Molecular chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
 
 0.896
msrB
Peptide-methionine (R)-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family.
    
 
 0.866
rpsI
Small subunit ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
   0.846
Your Current Organism:
Rugamonas rubra
NCBI taxonomy Id: 758825
Other names: ATCC 43154, CCM 3730, R. rubra, strain MOM 28/2/79
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