Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LSS_02474acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)    
Predicted Functional Partners:
LSS_02479
acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.991
LSS_10723
acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.971
LSS_01184
methylcrotonoyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.961
LSS_02484
Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.840
LSS_18698
biotin--acetyl-CoA-carboxylase ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.779
LSS_16796
Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.694
LSS_06260
ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.588
LSS_02489
Signal peptide protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.550
LSS_05468
2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
 0.503
LSS_11255
2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.503
Your Current Organism:
Leptospira santarosai
NCBI taxonomy Id: 758847
Other names: L. santarosai serovar Shermani str. LT 821, Leptospira santarosai serovar Shermani LT 821, Leptospira santarosai serovar Shermani str. ATCC 43286, Leptospira santarosai serovar Shermani str. LT 821, Leptospira santarosai serovar Shermani strain LT 821
Server load: low (12%) [HD]