Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LSS_03389Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)    
Predicted Functional Partners:
LSS_03379
Carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.695
LSS_03384
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.695
LSS_03394
GCN5 family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.647
tatA
Preprotein translocase subunit TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
  
 
 0.628
LSS_18054
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.623
LSS_03034
5-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
  
 0.543
LSS_04239
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.501
LSS_12959
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.501
LSS_03369
Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.407
LSS_03374
Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
       0.406
Your Current Organism:
Leptospira santarosai
NCBI taxonomy Id: 758847
Other names: L. santarosai serovar Shermani str. LT 821, Leptospira santarosai serovar Shermani LT 821, Leptospira santarosai serovar Shermani str. ATCC 43286, Leptospira santarosai serovar Shermani str. LT 821, Leptospira santarosai serovar Shermani strain LT 821
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.