Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LSS_04776Serine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (811 aa)    
Predicted Functional Partners:
argJ
Ornithine acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
     0.858
LSS_17145
Anti-sigma factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
  
   0.842
LSS_04781
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.840
LSS_02212
Anti-sigma factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
  
   0.813
LSS_10718
Antagonist of anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
  
   0.809
LSS_05628
Anti-sigma factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
  
   0.803
LSS_09404
Sigma factor PP2C phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.772
LSS_10388
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.749
LSS_09808
Anti-sigma factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.740
LSS_04796
PhoP family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.727
Your Current Organism:
Leptospira santarosai
NCBI taxonomy Id: 758847
Other names: L. santarosai serovar Shermani str. LT 821, Leptospira santarosai serovar Shermani LT 821, Leptospira santarosai serovar Shermani str. ATCC 43286, Leptospira santarosai serovar Shermani str. LT 821, Leptospira santarosai serovar Shermani strain LT 821
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