Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LSS_15596Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (246 aa)    
Predicted Functional Partners:
LSS_15591
CRISPR-associated protein Cse4; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.998
LSS_15581
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.997
LSS_15586
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.996
LSS_15576
Helicase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.990
LSS_15606
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
  
 0.976
LSS_11530
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
 0.937
cas1-2
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.910
LSS_15616
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
  
 0.899
LSS_15601
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
  
  
 0.522
Your Current Organism:
Leptospira santarosai
NCBI taxonomy Id: 758847
Other names: L. santarosai serovar Shermani str. LT 821, Leptospira santarosai serovar Shermani LT 821, Leptospira santarosai serovar Shermani str. ATCC 43286, Leptospira santarosai serovar Shermani str. LT 821, Leptospira santarosai serovar Shermani strain LT 821
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