Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LSS_22285Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (236 aa)    
Predicted Functional Partners:
LSS_22280
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.893
LSS_02939
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.813
LSS_04831
DNA mismatch repair protein MutT; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.800
LSS_20950
NTP pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Nudix hydrolase family.
  
 0.800
LSS_06440
RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family.
  
 0.789
LSS_12964
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family.
  
 0.789
groEL
Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.761
LSS_15216
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.653
LSS_09933
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.579
LSS_02669
Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
  
    0.570
Your Current Organism:
Leptospira santarosai
NCBI taxonomy Id: 758847
Other names: L. santarosai serovar Shermani str. LT 821, Leptospira santarosai serovar Shermani LT 821, Leptospira santarosai serovar Shermani str. ATCC 43286, Leptospira santarosai serovar Shermani str. LT 821, Leptospira santarosai serovar Shermani strain LT 821
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