STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHE95694.13-dehydroquinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal-type DHQ synthase family. (325 aa)    
Predicted Functional Partners:
AHE95409.1
Prephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.962
aroD
3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
  
  
  0.916
aroA
Fructose-bisphosphate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
 
  
 0.901
AHE95693.1
Glycosyltransferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
       0.773
AHE95696.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
crcB
Chromosome condensation protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.773
AHE95698.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
AHE95692.1
Pyrazinamidase/nicotinamidase pxnc; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.705
AHE95699.1
Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.628
Your Current Organism:
Thermocrinis ruber
NCBI taxonomy Id: 75906
Other names: DSM 23557, T. ruber, strain OC 1/4, strain OC 14/7/2
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